硼酸及其衍生物在熒光分子開關中的應用

熒光分子開關中主體和客體之間可以通過多種方式相結合,其中帶有熒光團的硼酸衍生
物與糖或羥基化合物的結合是通過共價鍵形成的。糖化學在生命科學中起著非常重要的作用,因此對糖的識別和檢測在醫(yī)學、細胞生物學等領域具有至關重要的意義。硼酸衍生物可以作為熒光分子開關對糖進行有效的選擇性識別,因而受到科學家們的廣泛關注。本文對近年來國內外相關研究成果進行了綜述。
關鍵詞　硼酸衍生物　熒光　開關　傳感器　糖
Abstract 　There are many types of combinations between the hosts and guests in fluorescent molecular switch. Among them , boric acid derivatives with fluorophore may selectively recognize saccharides or hydroxyl compounds through the formation of covalent bond. Since the chemistry of saccharides plays a significant role in life science , the recognition and detection of saccharides are very important in medicine , cellular , biological science and other fields. As a sort of efficient fluroescent molecular sensors , the boric acid derivatives are sensitive and selective in the recogni2 tion of some saccharides and have attracted extensive attentions of many chemists. In this context , the relative results of research about this type of fluroescent molecular switches in recent years were reviewed.
Key words 　Boric acid , Fluorescence , Switch , Sensor , Saccharide